The Boy in the Plastic Bubble

John Travolta

Tod Lubitch

Glynnis O'Connor

Gina Biggs

Robert Reed

Johnny Lubitch

Diana Hyland

Mickey Lubitch

Karen Morrow

Martha Biggs

Howard Platt

Neighbor

Buzz Aldrin

Himself

Ralph Bellamy

Dr. Gunther

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John Friedrich

Roy Slater

Kelly Ward

Tom Shuster

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Skip Lowell

Bruce Shuster

John Megna

Smith

Vernee Watson

Gwen

Darrell Zwerling

Mr. Brister

P. J. Soles

Deborah

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Timothy Himes

Obnoxious Reporter

Victor Brandt

TV Installer

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Hilda Haynes

The Nurse

Jack McLaughlin-Gray

Principal

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Erna Foxworth

Neighbor